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Clinical Roundup

APN401 CBL-B-silenced autologous cell therapy demonstrates favorable safety profile, phase I studies find

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APN401, an autologous PBMC (peripheral blood mononuclear cell) therapy, demonstrated a favorable safety profile, with no dose-limiting toxicities or grade ≥3 treatment-related adverse events, according to the results from two phase I studies evaluating APN401 in patients with advanced, treatment-refractory solid tumors.

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