Sylvester-led study focuses on rate of failure in head and neck cancer trials

Combination treatment may dramatically improve survival in brain cancer

A study suggests that laser interstitial thermal therapy using NeuroBlate may enhance the effectiveness of the immunotherapy drug pembrolizumab (Keytruda) for patients with recurrent high grade astrocytoma, including glioblastoma.

March 06, 2026

Vol.52 No.09

Guest Editorial

When radiology fails to fix clinical trial imaging workflow at sites…
What most think, why it’s wrong, and what cancer centers really need

Radiology departments have tried for years to “own” or “fix” clinical trials imaging assessment workflows by extending clinical tools (PACS, worklists, dictation systems) and habits (speed, seamlessness, few clicks) into the research world.

NHS-Galleri MCD trial fails to meet primary endpoint of stage shift

High-level results from the randomized, controlled NHS-Galleri trial, which is evaluating GRAIL’s multi-cancer screening test, Galleri, over three years in 142,000 participants aged 50 to 77, reveals that the trial did not meet its primary endpoint of shifting cancer diagnosis from advanced stages (3 and 4) to earlier stage (1 and 2).

Rybrevant Faspro + immunotherapy shows strong clinical benefit for recurrent or metastatic head-and-neck cancer

Data from the phase Ib/II OrigAMI-4 study found that first-line treatment with investigational subcutaneous amivantamab and hyaluronidase-lpuj in combination with a PD-1 inhibitor delivered clinically meaningful and durable antitumor activity in patients with head and neck squamous cell carcinoma that is recurrent or metastatic, PD-L1-positive, and HPV-unrelated.

February 27, 2026

Vol.52 No.08

Clinical Roundup

“Lock-and-key” chemistry platform may keep therapeutic drugs inactive until they reach a tumor, Syracuse-led study finds

Many therapeutic molecules used in cancer treatments are highly toxic, often harming healthy tissues and causing significant side effects. This creates a critical need for strategies that localize their toxic activity to tumors. What if cancer drugs could stay dormant until they reach cancer cells? A study by Syracuse University researchers demonstrates a promising chemistry-based strategy that could do just that.

February 27, 2026

Vol.52 No.08

Clinical Roundup

Exercise during chemotherapy for breast cancer improves quality of life, Sylvester-led study finds

For many women with breast cancer, the treatment that saves their lives also brings fatigue that clings like a heavy coat, loss of muscle mass that turns everyday tasks into obstacles and emotional strain that lingers long after each infusion ends. It’s a season defined not just by survival, but by how well patients are able to live through it.

February 27, 2026

Vol.52 No.08

Sylvester-led study focuses on rate of failure in head and neck cancer trials

YOU MAY BE INTERESTED IN

Combination treatment may dramatically improve survival in brain cancer

When radiology fails to fix clinical trial imaging workflow at sites…
What most think, why it’s wrong, and what cancer centers really need

NHS-Galleri MCD trial fails to meet primary endpoint of stage shift

Rybrevant Faspro + immunotherapy shows strong clinical benefit for recurrent or metastatic head-and-neck cancer

“Lock-and-key” chemistry platform may keep therapeutic drugs inactive until they reach a tumor, Syracuse-led study finds

Exercise during chemotherapy for breast cancer improves quality of life, Sylvester-led study finds

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Sylvester-led study focuses on rate of failure in head and neck cancer trials

YOU MAY BE INTERESTED IN

Combination treatment may dramatically improve survival in brain cancer

When radiology fails to fix clinical trial imaging workflow at sites…What most think, why it’s wrong, and what cancer centers really need

NHS-Galleri MCD trial fails to meet primary endpoint of stage shift

Rybrevant Faspro + immunotherapy shows strong clinical benefit for recurrent or metastatic head-and-neck cancer

“Lock-and-key” chemistry platform may keep therapeutic drugs inactive until they reach a tumor, Syracuse-led study finds

Exercise during chemotherapy for breast cancer improves quality of life, Sylvester-led study finds

Never miss an issue!

Login

When radiology fails to fix clinical trial imaging workflow at sites…
What most think, why it’s wrong, and what cancer centers really need