Off-the-shelf cancer vaccine elicits strong immune response in patients with pancreatic and colorectal cancer

Hepatitis B vaccine birth dose down 2% in children under 2 years old, CDC immunization report finds

Immunization rates are declining in infants and toddlers 24 months and younger, according to the most recent National Immunization Survey-Child report from the Centers for Disease Control and Prevention.

April 03, 2026

Vol.52 No.13

By Sara Willa Ernst

Clinical Trials & Tribulations

Early-onset cancer is on the rise. Here is how OSUCCC–James is adapting to the needs of younger patients

The incidence of multiple cancer types in people under the age of 50 has been rising, with early-onset cancers now contributing to nearly 15,000 excess cases of cancer in the U.S. annually.

March 27, 2026

Vol.52 No.12

By W. Kimryn Rathmell

Trials & Tribulations

In the era of immunotherapy, response rate alone fails to predict true patient benefit
Regulators must adapt

March is National Colorectal Cancer Awareness Month. It is a reminder of a heartbreaking trend that oncologists like me are witnessing in our clinics: Last year, for the first time, colorectal cancer became the leading cause of cancer-related death in Americans under the age of 50, according to data published earlier this year in JAMA.

March 27, 2026

Vol.52 No.12

By Richard M. Goldberg

Clinical

Colorectal cancer is now the leading cause of cancer death in patients under 50
Why aren’t 45-year-olds getting their recommended CRC screenings?

Three decades ago, colorectal cancer was the fifth leading cause of cancer death in patients under 50 years old. For a physician treating the average 45-year-old, colorectal cancer was not a diagnosis that immediately came to mind.

At a jam-packed NCAB meeting, cancer vaccines and site visits take center stage

Last week’s issue of The Cancer Letter was dominated by one event: the meeting of the National Cancer Advisory Board, the group of experts which advises and assists the NCI director on the activities of the National Cancer Program.

March 25, 2026

Early-onset colorectal cancer demands a new research playbook

Colorectal cancer is no longer a disease confined to older adults.

March 20, 2026

Vol.52 No.11

By Marwan Fakih

Off-the-shelf cancer vaccine elicits strong immune response in patients with pancreatic and colorectal cancer

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Hepatitis B vaccine birth dose down 2% in children under 2 years old, CDC immunization report finds

Early-onset cancer is on the rise. Here is how OSUCCC–James is adapting to the needs of younger patients

In the era of immunotherapy, response rate alone fails to predict true patient benefit
Regulators must adapt

Colorectal cancer is now the leading cause of cancer death in patients under 50
Why aren’t 45-year-olds getting their recommended CRC screenings?

At a jam-packed NCAB meeting, cancer vaccines and site visits take center stage

Early-onset colorectal cancer demands a new research playbook

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Off-the-shelf cancer vaccine elicits strong immune response in patients with pancreatic and colorectal cancer

YOU MAY BE INTERESTED IN

Hepatitis B vaccine birth dose down 2% in children under 2 years old, CDC immunization report finds

Early-onset cancer is on the rise. Here is how OSUCCC–James is adapting to the needs of younger patients

In the era of immunotherapy, response rate alone fails to predict true patient benefitRegulators must adapt

Colorectal cancer is now the leading cause of cancer death in patients under 50Why aren’t 45-year-olds getting their recommended CRC screenings?

At a jam-packed NCAB meeting, cancer vaccines and site visits take center stage

Early-onset colorectal cancer demands a new research playbook

Never miss an issue!

Login

In the era of immunotherapy, response rate alone fails to predict true patient benefit
Regulators must adapt

Colorectal cancer is now the leading cause of cancer death in patients under 50
Why aren’t 45-year-olds getting their recommended CRC screenings?