Individuals with cannabis use disorder are more than three times more likely to develop oral cancer within five years compared to those without CUD, a researcher at the University of California San Diego School of Medicine found.
Epidermal growth factor receptor signaling in the tissue around oral cancers both increases nerve sensitivity and makes opioids less effective, according to a study conducted by researchers at NYU, MD Anderson, and Loma Linda University. The finding points to a shared mechanism underlying both oral cancer pain and opioid tolerance, and a possible new treatment strategy for both.
