Immunotherapy for pediatric osteosarcoma with lung metastases after resection shows positive data

Combination treatment may dramatically improve survival in brain cancer

A study suggests that laser interstitial thermal therapy using NeuroBlate may enhance the effectiveness of the immunotherapy drug pembrolizumab (Keytruda) for patients with recurrent high grade astrocytoma, including glioblastoma.

March 06, 2026

Vol.52 No.09

Guest Editorial

When radiology fails to fix clinical trial imaging workflow at sites…
What most think, why it’s wrong, and what cancer centers really need

Radiology departments have tried for years to “own” or “fix” clinical trials imaging assessment workflows by extending clinical tools (PACS, worklists, dictation systems) and habits (speed, seamlessness, few clicks) into the research world.

NHS-Galleri MCD trial fails to meet primary endpoint of stage shift

High-level results from the randomized, controlled NHS-Galleri trial, which is evaluating GRAIL’s multi-cancer screening test, Galleri, over three years in 142,000 participants aged 50 to 77, reveals that the trial did not meet its primary endpoint of shifting cancer diagnosis from advanced stages (3 and 4) to earlier stage (1 and 2).

Rybrevant Faspro + immunotherapy shows strong clinical benefit for recurrent or metastatic head-and-neck cancer

Data from the phase Ib/II OrigAMI-4 study found that first-line treatment with investigational subcutaneous amivantamab and hyaluronidase-lpuj in combination with a PD-1 inhibitor delivered clinically meaningful and durable antitumor activity in patients with head and neck squamous cell carcinoma that is recurrent or metastatic, PD-L1-positive, and HPV-unrelated.

February 27, 2026

Vol.52 No.08

Clinical Roundup

Adjuvant immunotherapy + hormone therapy may counteract immune-suppression in early-stage prostate cancer, Mayo-led study finds

Pairing a next-generation immunotherapy with standard hormone therapy before surgery may help overcome a long-standing barrier in early-stage prostate cancer treatment, according to a Mayo Clinic-led study.

February 27, 2026

Vol.52 No.08

In Brief

James Downing to step down as president and CEO of St. Jude to focus on global pediatric medicine

After leading unprecedented growth of St. Jude Children’s Research Hospital over the past 12 years, James R. Downing will step down as president and CEO in late 2026 as part of a planned leadership transition, St. Jude officials said.

February 20, 2026

Vol.52 No.07

Immunotherapy for pediatric osteosarcoma with lung metastases after resection shows positive data

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Combination treatment may dramatically improve survival in brain cancer

When radiology fails to fix clinical trial imaging workflow at sites…
What most think, why it’s wrong, and what cancer centers really need

NHS-Galleri MCD trial fails to meet primary endpoint of stage shift

Rybrevant Faspro + immunotherapy shows strong clinical benefit for recurrent or metastatic head-and-neck cancer

Adjuvant immunotherapy + hormone therapy may counteract immune-suppression in early-stage prostate cancer, Mayo-led study finds

James Downing to step down as president and CEO of St. Jude to focus on global pediatric medicine

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Immunotherapy for pediatric osteosarcoma with lung metastases after resection shows positive data

YOU MAY BE INTERESTED IN

Combination treatment may dramatically improve survival in brain cancer

When radiology fails to fix clinical trial imaging workflow at sites…What most think, why it’s wrong, and what cancer centers really need

NHS-Galleri MCD trial fails to meet primary endpoint of stage shift

Rybrevant Faspro + immunotherapy shows strong clinical benefit for recurrent or metastatic head-and-neck cancer

Adjuvant immunotherapy + hormone therapy may counteract immune-suppression in early-stage prostate cancer, Mayo-led study finds

James Downing to step down as president and CEO of St. Jude to focus on global pediatric medicine

Never miss an issue!

Login

When radiology fails to fix clinical trial imaging workflow at sites…
What most think, why it’s wrong, and what cancer centers really need