UT Health San Antonio creates pancreatic cancer organoid

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A study by scientists at the University of Texas Health Science Center at San Antonio provides one of the first models to study the progression of normal human pancreatic cells toward tumor cells. 

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In a phase II clinical trial, a research team led by Nilofer Azad, professor of oncology and co-leader of the Kimmel Cancer Center’s Cancer Genetics and Epigenetics Program, and Marina Baretti, the Jiasheng Chair in Hepato-Biliary Cancer at the Kimmel Cancer Center, tested the safety and efficacy of the combination of two drugs: an immunotherapy, nivolumab, and an epigenetic drug, entinostat—a histone deacetylase inhibitor. 

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