The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Data from phase I/II study shows Rina-S improves ORR for treatment of ovarian cancer

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Data from the phase I/II study of Rina-S (rinatabart sesutecan), an investigational folate receptor-alpha-targeted, Topo1 antibody-drug conjugate, demonstrated a confirmed objective response rate of 50.0% (95% CI) in ovarian cancer patients treated with Rina-S 120 mg/m2 once every three weeks, regardless of FRα expression levels. 

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