Phase II study of personalized cancer vaccine in CRC shows positive preliminary PFS and long-term ctDNA data

Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic, and triple-negative breast cancer in mice.

October 17, 2025

Vol.51 No.38

Cancer Policy

CDC updates childhood vaccine recommendations

Jim O’Neill, acting director of the Centers for Disease Control and Prevention, announced that he has signed off on a slew of recommendations that change the childhood vaccination schedule.

October 10, 2025

Vol.51 No.37

By Claire Marie Porter

Clinical Roundup

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts that appear to support the survival and growth of malignant tumors.

October 10, 2025

Vol.51 No.37

In Brief

Alessio Pigazzi, expert in robot-assisted techniques, selected as new colorectal surgery leader at Cedars-Sinai

Alessio Pigazzi was chosen to lead the newly created faculty division of colorectal surgery in the Jim and Eleanor Randall Department of Surgery at Cedars-Sinai.

October 03, 2025

Vol.51 No.36

In Brief

The University of Cincinnati researchers win NCI grant to study combination colorectal cancer treatment

The University of Cincinnati Cancer Center’s Joan Garrett has received a two-year, $162,000 NCI grant to study a new combination approach to treat KRAS-mutated colorectal cancers.

October 03, 2025

Vol.51 No.36

Clinical Roundup

Korean researchers find CRC patients over 70 years don’t stand to benefit from chemo

Oxaliplatin-based chemotherapy significantly improves survival only in stage 3 colorectal cancer patients aged 70 or younger, according to a study conducted by researchers at Korea University Guro Hospital and Korea University College of Medicine. For patients over 70, the drug offered no survival advantage and led to higher rates of treatment discontinuation due to toxicity.

September 26, 2025

Vol.51 No.35

Phase II study of personalized cancer vaccine in CRC shows positive preliminary PFS and long-term ctDNA data

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Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

CDC updates childhood vaccine recommendations

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

Alessio Pigazzi, expert in robot-assisted techniques, selected as new colorectal surgery leader at Cedars-Sinai

The University of Cincinnati researchers win NCI grant to study combination colorectal cancer treatment

Korean researchers find CRC patients over 70 years don’t stand to benefit from chemo

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