The ongoing, signal-seeking phase II portion of the phase II/III study evaluating Granite, a personalized neoantigen cancer vaccine, in front-line metastatic microsatellite stable colorectal cancer, produced positive preliminary data.
Oxaliplatin-based chemotherapy significantly improves survival only in stage 3 colorectal cancer patients aged 70 or younger, according to a study conducted by researchers at Korea University Guro Hospital and Korea University College of Medicine. For patients over 70, the drug offered no survival advantage and led to higher rates of treatment discontinuation due to toxicity.
