The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Datopotamab deruxtecan improves PFS in advanced NSCLC, phase III trial shows

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Positive high-level results from the TROPION-Lung01 phase III trial showed datopotamab deruxtecan (Dato-DXd) demonstrated a statistically significant improvement for the dual primary endpoint of progression-free survival compared to docetaxel, the current standard of care chemotherapy, in patients with locally advanced or metastatic non-small cell lung cancer treated with at least one prior therapy.

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