HERGain study shows potential for chemotherapy-free treatment of early HER2+ breast cancer

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In the phase II PHERGain study, 95.4% of patients who followed a chemotherapy de-escalation strategy using PHERGain’s adaptive design remained cancer-free after three years of follow-up, and around 30% of patients responded to a fully chemotherapy-free regimen as part of their treatment for HER2- positive breast cancer. 

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From left to right: Geoffrey Shapiro, Leif Ellisen and Nancy Lin. Sitting below them is Kornelia Polyak.The Dana-Farber/Harvard Cancer Center,  a cancer research consortium comprised of five of Boston’s academic medical centers, including Dana-Farber Cancer Institute and Massachusetts General Hospital, has been awarded an NCI grant to continue its Specialized Program of Research Excellence in Breast Cancer.

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