UCLA researchers use “rapid autopsies” to identify lethal molecular alterations in relapsed metastatic melanoma

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In a translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the organs of recently deceased patients to understand how metastatic cutaneous melanoma spreads in those who had initially benefited from precision therapies. 

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Mina Sedrak, associate professor of medicine at the David Geffen School of Medicine at UCLA and director of the Cancer and Aging Program at the UCLA Health Jonsson Comprehensive Cancer Center, received a five-year, $3.4 million grant from NIH to examine how exercise and certain drugs may be able to slow chemotherapy-related accelerated aging seen in breast cancer survivors.