Rutgers study: Expanded use of a personalized remote risk communication intervention increased uptake of genetic counseling

Study uncovers source of genetic variation influencing childhood brain tumors

Researchers at Baylor College of Medicine and collaborating institutions investigated for the first time in cancer the association between two sources of genetic variation: germline or inherited structural variation, which refers to large differences in the DNA sequence, and DNA methylation, which is when genes are turned on or off without altering the DNA code.

May 23, 2025

Vol.51 No.20

Clinical Roundup

Genetic mutation in some Ashkenazi Jewish men may be linked to higher prostate cancer risk, study shows

A Johns Hopkins Medicine-led research team has identified a recurrent frameshift mutation, called F722fs, in the MMS22L gene among men of Ashkenazi Jewish ancestry that is associated with a higher risk of prostate cancer and increased sensitivity to a specific anticancer therapy.

May 23, 2025

Vol.51 No.20

In Brief

RWJBarnabas Health, Rutgers open NJ’s first and only freestanding cancer hospital

RWJBarnabas Health and Rutgers Cancer Institute, the state’s only NCI-designated Comprehensive Cancer Center, have opened New Jersey’s first and only freestanding, fully comprehensive cancer hospital (The Cancer Letter, April 25, 2025).

May 16, 2025

Vol.51 No.19

Conversation with The Cancer Letter

Steven Libutti tells us about building a $900 million cancer hospital for Rutgers RWJBarnabas Health

Over the past seven years, as Steven K. Libutti was designing the 12-story, $900-plus million cancer hospital in New Brunswick, NJ, he often thought of the functionality of the building that inspired it: Building 10, the NIH Clinical Center.

April 25, 2025

Vol.51 No.16

By Paul Goldberg

Trials & Tribulations

Genetic counseling can improve genetic screening and accelerate clinical trial success

In an effort to target the right patients, genetic screening is becoming more common in clinical trials. But incorporating it can be complex and add a significant burden for both patients and clinical trial sites. Genetic counseling can streamline that process and help drug and gene therapy developers expedite the recruitment of genetically-eligible participants for their trials and use genetic testing results to accelerate the speed and success of clinical trials.

David Liu awarded 2025 Breakthrough Prize in Life Sciences

Howard Hughes Medical Institute Investigator David R. Liu was awarded the 2025 Breakthrough Prize in Life Sciences for developing two gene-editing technologies—known as base editing and prime editing—which enable the correction or replacement of virtually any genetic mutation, including those that cause countless human genetic diseases.

April 11, 2025

Vol.51 No.14

Rutgers study: Expanded use of a personalized remote risk communication intervention increased uptake of genetic counseling

YOU MAY BE INTERESTED IN

Study uncovers source of genetic variation influencing childhood brain tumors

Genetic mutation in some Ashkenazi Jewish men may be linked to higher prostate cancer risk, study shows

RWJBarnabas Health, Rutgers open NJ’s first and only freestanding cancer hospital

Steven Libutti tells us about building a $900 million cancer hospital for Rutgers RWJBarnabas Health

Genetic counseling can improve genetic screening and accelerate clinical trial success

David Liu awarded 2025 Breakthrough Prize in Life Sciences

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