The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Lung cancer study finds new target for treatment resistance after EGFR inhibitors

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Researchers at MD Anderson Cancer Center have identified CD70 as being highly expressed on drug-resistant cancer cells in EGFR-mutant non-small cell lung cancer, highlighting a novel therapeutic target that could be used to eliminate resistant cells remaining after treatment with commonly used EGFR tyrosine kinase inhibitors. The study was published in Cancer Cell.

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