In findings led by researchers at Yale Cancer Center and collaborating institutions, the monoclonal antibody drug sotigalimab, combined with Bristol Myers Squibb’s immunotherapy drug Opdivo (nivolumab), resulted in tumor shrinkage in patients with advanced melanoma whose tumors had progressed on prior immunotherapy.
Research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient’s T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer.
