Virus-mimicking drug helps immune system target cunning cancer cells

Neoadjuvant dostarlimab averts brutal surgery in 80% of patients with dMMR solid tumors

Three years ago, researchers from Memorial Sloan Kettering Cancer Center published stunning results: For the 5% of rectal cancer patients whose tumors are mismatch-repair deficient, neoadjuvant dostarlimab-gxly (Jemperli) has the makings of a silver bullet.

May 02, 2025

By Jacquelyn Cobb

Clinical

Kelly Spill opted for dostarlimab trial, avoiding rectal cancer treatment that would leave her infertile
Six years later, she is well—and pregnant with her third child

When Kelly Spill was eight months pregnant, she experienced some constipation and noticed blood in her stool. Her OBGYN wasn’t worried.

May 02, 2025

By Jacquelyn Cobb

White House

The White House “skinny budget” document cuts NIH by nearly 40%
The cuts are consistent with the previously leaked “passback” document

An updated version of President Trump’s budget request published on May 2 comes as a disappointment for those who hoped that the White House would rethink the draconian cuts contained in an earlier, confidential version of the document that ended up being leaked to the press.

May 02, 2025

By Jacquelyn Cobb and Claire Marie Porter

News Analysis

NIH eliminates the NCI Board of Scientific Advisors
Over its 28 year history, BSA shaped NCI-funded extramural science

After nearly three decades of reviewing NCI-funded extramural projects and sometimes saving NCI from its own folly, the Board of Scientific Advisors has been terminated as part of the Trump administration’s drive to reduce the size of the federal government.

May 02, 2025

By Paul Goldberg

Bertagnolli: NIH funding cuts are “unprecedented and harmful”
AACR panel challenges scientists to find stability in a period of “ventricular tachycardia”

“We stand at the edge of discovery, and on the brink of losing it,” said Patricia M. LoRusso, the 2024-2025 president of the American Association for Cancer Research. “I believe this is the most scientifically promising moment in the history of cancer research.”

May 02, 2025

By Claire Marie Porter

Advancing quality of life in oncology: A journey of compassion and innovation

The recent ASCO guideline update on palliative care for cancer patients represents a significant milestone in our field’s evolution. This evidence-based guidance emphasizes what I’ve advocated throughout my career—that palliative care must be integrated early and concurrently throughout the cancer journey. This holistic approach to cancer care has been my life’s work and passion.

May 02, 2025

By Betty Ferrell

Virus-mimicking drug helps immune system target cunning cancer cells

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Neoadjuvant dostarlimab averts brutal surgery in 80% of patients with dMMR solid tumors

Kelly Spill opted for dostarlimab trial, avoiding rectal cancer treatment that would leave her infertile
Six years later, she is well—and pregnant with her third child

The White House “skinny budget” document cuts NIH by nearly 40%
The cuts are consistent with the previously leaked “passback” document

NIH eliminates the NCI Board of Scientific Advisors
Over its 28 year history, BSA shaped NCI-funded extramural science

Bertagnolli: NIH funding cuts are “unprecedented and harmful”
AACR panel challenges scientists to find stability in a period of “ventricular tachycardia”

Advancing quality of life in oncology: A journey of compassion and innovation

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Virus-mimicking drug helps immune system target cunning cancer cells

YOU MAY BE INTERESTED IN

Neoadjuvant dostarlimab averts brutal surgery in 80% of patients with dMMR solid tumors

Kelly Spill opted for dostarlimab trial, avoiding rectal cancer treatment that would leave her infertileSix years later, she is well—and pregnant with her third child

The White House “skinny budget” document cuts NIH by nearly 40%The cuts are consistent with the previously leaked “passback” document

NIH eliminates the NCI Board of Scientific AdvisorsOver its 28 year history, BSA shaped NCI-funded extramural science

Bertagnolli: NIH funding cuts are “unprecedented and harmful”AACR panel challenges scientists to find stability in a period of “ventricular tachycardia”

Advancing quality of life in oncology: A journey of compassion and innovation

Never miss an issue!

Login

Kelly Spill opted for dostarlimab trial, avoiding rectal cancer treatment that would leave her infertile
Six years later, she is well—and pregnant with her third child

The White House “skinny budget” document cuts NIH by nearly 40%
The cuts are consistent with the previously leaked “passback” document

NIH eliminates the NCI Board of Scientific Advisors
Over its 28 year history, BSA shaped NCI-funded extramural science

Bertagnolli: NIH funding cuts are “unprecedented and harmful”
AACR panel challenges scientists to find stability in a period of “ventricular tachycardia”