The Cancer Letter

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Clinical Roundup

OS and PFS for Keytruda in hepatocellular carcinoma did not meet statistical significance

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Merck announced the pivotal phase III KEYNOTE-240 trial evaluating Keytruda, Merck’s anti-PD-1 therapy, plus best supportive care, for the treatment of patients with advanced hepatocellular carcinoma who were previously treated with systemic therapy, did not meet its co-primary endpoints of overall survival and progression-free survival compared with placebo plus best supportive care.

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