The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Keytruda-Inlyta combination improved OS and PFS in front line for advanced, metastatic RCC

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The pivotal phase III KEYNOTE-426 trial investigating Keytruda (pembrolizumab), Merck’s anti-PD-1 therapy, in combination with Inlyta (axitinib), Pfizer’s tyrosine kinase inhibitor, met both primary endpoints of overall survival and progression-free survival in the first-line treatment of advanced or metastatic renal cell carcinoma.

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