publication date: Jul. 2, 2020

NCI Trials

NCI Trials for July 2020

The National Cancer Institute approved the following clinical research studies last month. 

For further information, contact the principal investigator listed.


Phase I – 10327

A Phase I Trial of  MLN0128 (Sapanisertib) and CB-839 HCL (Telaglenastat) in Advanced NSCLC Patients

City of Hope Comprehensive Cancer Center LAO

Riess, Jonathan W.

(916) 734-3772


Phase I – 10335

A Phase 1 Study of Lenalidomide in Combination with EPOCH Chemotherapy for HTLV-Associated Adult T-Cell Leukemia-Lymphoma (ATLL)

Yale University Cancer Center LAO

Ratner, Lee

(314) 362-8836


Phase I – 10349

A Phase I Trial of the P97 Inhibitor CB-5339 in Patients with Advanced Solid Tumors and Lymphomas

National Cancer Institute LAO

Takebe, Naoko

(240) 781-3398


Phase I – 10388

A Phase I Trial of Triapine and Lutetium Lu 177 Dotatate in Combination for Well-Differentiated Somatostatin Receptor-Positive Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)

Ohio State University Comprehensive Cancer Center LAO

Chauhan, Aman

(504) 278-0134


Phase II – 10211

A Phase 2 Single-Arm Study of M6620 in Combination with Irinotecan in Patients with Progressive TP53 Mutant Gastric and Gastro-Esophageal Junction Cancer

Yale University Cancer Center LAO

Berlin, Jordan D.

(615) 343-4128


Phase II – APEC1621N

NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) – Phase 2 Subprotocol of LOXO-292 in Patients with Tumors Harboring RET Gene Alterations

Children’s Oncology Group

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