publication date: Jul. 31, 2014


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NCI CTEP-Approved Trials for the Month of July


The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. For further information, contact the principal investigator listed.


Phase I

ADVL1314: A Phase 1 Study of Eribulin Mesylate (E7389, IND#116,292), a Novel Microtubule Targeting Chemotherapeutic Agent in Children with Refractory or Recurrent Solid Tumors (Excluding CNS), Including Lymphomas. COG Phase 1 Consortium; Schafer, Eric Stephen. (832) 825-4241

ADVL1315: A Phase 1 Study of the VEGF Receptor Tyrosine Kinase Inhibitor Axitinib (INLYTA, IND# TBD) in Children with Recurrent or Refractory Solid Tumors. COG Phase 1 Consortium; Geller, James Ian. (513) 636-6312


Phase I/II

EA2131: A Phase I and Randomized, Double-Blinded Phase II Study of Nab-Paclitaxel/Gemcitabine Plus AZD1775 or Placebo in Treatment-Naïve Metastatic Adenocarcinoma of the Pancreas. ECOG-ACRIN Cancer Research Group; Chee, Cheng Ean. (216) 844-8609


Phase II

9604: Perfusion CT as Predictive Biomarker in a Phase II Study of Ziv-Aflibercept in Patients with Advanced Pancreatic Neuroendocrine Tumors. MD Anderson Cancer Center; Yao, James C. (713) 792-2828

S1300: A Randomized, Phase II Trial of Crizotinib Plus Pemetrexed Versus Pemetrexed Monotherapy in ALK-Positive Non-Squamous NSCLC Patients Who Have Progressed Systemically After Previous Clinical Benefit From Crizotinib Monotherapy. SWOG; Camidge, David Ross. (720) 848-0449

S1320: A Randomized Phase II Trial of Intermittent Versus Continuous Dosing of Dabrafenib (NSC-763760) and Trametinib (NSC-763093) in BRAF V600E/K Mutant Melanoma. SWOG; Algazi, Alain Patrick. (415) 353-7552


Phase II/III

ARST1321: … Continue reading CCL July – NCI CTEP-Approved Trials for the Month of July

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