City of Hope awarded $23.7M from ARPA-H for biomarker mapping

Moving beyond escalation to a new therapeutic strategy in oncology
Microbiome-based treatment may offer a different approach

Cancer therapy has become increasingly personalized. Biomarker-driven treatment selection, targeted therapies, and immunotherapy have transformed outcomes across many tumor types and demonstrated the power of matching the right treatment to the right patient.

October 23, 2026

Vol.52 No.39

By Sumanta Pal

Clinical Roundup

Researchers uncovers immune driver of radiation-related lung injury, City of Hope-led preclinical study finds

Researchers at City of Hope have uncovered an immune pathway that may contribute to radiation-related lung damage and have identified a potential strategy to block it. The insights from the preclinical study could lead to treatments that prevent radiation from harming healthy lung tissue and improve patients’ quality of life.

October 23, 2026

Vol.52 No.39

Podcast

As USPSTF falters, the idea that “screening is always good” is gaining traction

With the pope’s lung cancer diagnosis jumpstarting conversations about lung cancer screening and the constant buzz surrounding multi-cancer detection tests, evidence-based evaluation of screening tests is more important than ever.

October 21, 2026

News Analysis

The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening
“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”

Pope Leo XIV has been diagnosed with lung adenocarcinoma. According to missives from the Holy See, the pope underwent surgery to remove the lower lobe of his right lung Oct. 13.

Cigarette smoke may prime lung stem cells for different types of lung cancer, Hopkins study finds

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene alterations and ultimately helps determine the type of lung cancer that develops.

October 09, 2026

Vol.52 No.37

Clinical Roundup

City of Hope’s “plug-and-play” CAR T platform lets researchers update cells after infusion

Researchers from City of Hope have developed a “plug-and-play” technology that adds engineered molecules to chimeric antigen receptor T cells after treatment, allowing scientists to better control the cells and redirect them to attack different types of cancer. The preclinical study offers a more flexible way to help CAR T cells keep pace with mutating tumors.

October 02, 2026

Vol.52 No.36

City of Hope awarded $23.7M from ARPA-H for biomarker mapping

YOU MAY BE INTERESTED IN

Moving beyond escalation to a new therapeutic strategy in oncology
Microbiome-based treatment may offer a different approach

Researchers uncovers immune driver of radiation-related lung injury, City of Hope-led preclinical study finds

As USPSTF falters, the idea that “screening is always good” is gaining traction

The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening
“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”

Cigarette smoke may prime lung stem cells for different types of lung cancer, Hopkins study finds

City of Hope’s “plug-and-play” CAR T platform lets researchers update cells after infusion

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City of Hope awarded $23.7M from ARPA-H for biomarker mapping

YOU MAY BE INTERESTED IN

Moving beyond escalation to a new therapeutic strategy in oncologyMicrobiome-based treatment may offer a different approach

Researchers uncovers immune driver of radiation-related lung injury, City of Hope-led preclinical study finds

As USPSTF falters, the idea that “screening is always good” is gaining traction

The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”

Cigarette smoke may prime lung stem cells for different types of lung cancer, Hopkins study finds

City of Hope’s “plug-and-play” CAR T platform lets researchers update cells after infusion

Never miss an issue!

Login

Moving beyond escalation to a new therapeutic strategy in oncology
Microbiome-based treatment may offer a different approach

The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening
“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”