Of adaptive and factorial designs

A biostatistician’s interpretation of last week’s ODAC

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At its most recent meeting, the FDA Oncologic Drugs Advisory Committee focused on perioperative clinical trials, which the agency defined as neoadjuvant phase followed by surgery and continuing with adjuvant treatment using the same experimental agent (The Cancer Letter, July 26, 2024).

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Donald A. Berry, PhD
Professor and founding chair, Department of Biostatistics, Founding head, Division of Quantitative Sciences, MD Anderson Cancer Center; Senior statistical consultant and founder, Berry Consultants, LLC
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Donald A. Berry, PhD
Professor and founding chair, Department of Biostatistics, Founding head, Division of Quantitative Sciences, MD Anderson Cancer Center; Senior statistical consultant and founder, Berry Consultants, LLC

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