Researchers develop molecular design for enhanced efficacy and safety in radiotheranostics

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Radiotheranostics is an approach that involves the use of a single radioactive agent for disease diagnosis and treatment. However, the use of low-molecular-weight proteins and peptides can lead to unwanted accumulation of the associated radioactive metabolites in the kidneys, which interferes with diagnostic accuracy and may cause side effects. Researchers from Japan recently overcame this limitation by developing novel radiolabeled antibody fragments capable of enhancing overall treatment outcomes and imaging accuracy.

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