Yale study finds rates of PSA testing for prostate cancer increased after revised national guidelines

ASTRO updates guideline on shorter-course radiation therapy for localized prostate cancer

An updated clinical guideline from the American Society for Radiation Oncology provides evidence-based recommendations on the use of hypofractionated radiation therapy for patients with localized prostate cancer.

October 30, 2026

Vol.52 No.40

Clinical Roundup

Perioperative apalutamide in high-risk localized or locally advanced prostate cancer substudy supports reduced risk of metastasis and death

An international phase III clinical trial that treated patients with high-risk localized and locally advanced prostate cancer with apalutamide—a next-generation neoadjuvant androgen-receptor pathway inhibitor—plus hormone therapy before and after prostate cancer surgery, was further validated by a substudy demonstrating a reduced risk of metastasis or death compared with standard of care.

October 30, 2026

Vol.52 No.40

Drugs & Targets

FDA expands approval of Talzenna + Xtandi for an earlier metastatic prostate cancer treatment setting

FDA has expanded approval of Talzenna (talazoparib) in combination with Xtandi (enzalutamide) for the treatment of men with metastatic androgen pathway modulation-naïve or -sensitive prostate cancer with homologous recombination repair gene mutations, including both BRCA and non-BRCA mutations.

October 30, 2026

Vol.52 No.40

Clinical Roundup

NCCN publishes guidelines for pediatric Ewing sarcoma

The National Comprehensive Cancer Network published the first-ever edition of NCCN Clinical Practice Guidelines in Oncology for Pediatric Bone Sarcoma.

October 09, 2026

Vol.52 No.37

Clinical Roundup

Decipher prostate test predicts benefit from adding hormone therapy to radiation, phase III trial shows

Decipher Prostate Genomic Classifier can predict which patients are more likely to benefit from adding short-term ADT, or androgen deprivation therapy, to dose-escalated radiation, providing both Level 1B1 prognostic and predictive evidence, according to a retrospective ancillary analysis of the randomized phase III NRG/RTOG 0815 trial.

October 02, 2026

Vol.52 No.36

Clinical Roundup

ASCO expresses support for functional precision medicine, rescinding past objections

The American Society of Clinical Oncology has expressed support for the advancement of functional precision medicine.

September 18, 2026

Vol.52 No.34

Yale study finds rates of PSA testing for prostate cancer increased after revised national guidelines

YOU MAY BE INTERESTED IN

ASTRO updates guideline on shorter-course radiation therapy for localized prostate cancer

Perioperative apalutamide in high-risk localized or locally advanced prostate cancer substudy supports reduced risk of metastasis and death

FDA expands approval of Talzenna + Xtandi for an earlier metastatic prostate cancer treatment setting

NCCN publishes guidelines for pediatric Ewing sarcoma

Decipher prostate test predicts benefit from adding hormone therapy to radiation, phase III trial shows

ASCO expresses support for functional precision medicine, rescinding past objections

Renew today!

Subscriber content

Never miss an issue!

Login