The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month.
For further information, contact the principal investigator listed.
Phase I – ABTC-1701
Pilot Surgical PK Study of BGB324 in Recurrent Glioblastoma Patients
Adult Brain Tumor Consortium
Nakano, Ichiro
(205) 934-1813
Phase I/II – 10096
A Phase 1/2 Study of Combination Olaparib and Radium-223 in Men with Metastatic Castration-Resistant Prostate Cancer with Bone Metastases (COMRADE)
Yale University Cancer Center LAO
McKay, Rana Ramzi
(858) 822-6185
Phase II – 10144
A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma with DNA-Repair Defects
National Cancer Institute LAO
Apolo, Andrea Borghese
(301) 480-0536
Phase II – AMC-102
A Randomized Phase II Trial of Concurrent Chemotherapy and Pelvic Radiation Therapy with or Without Paclitaxel and Carboplatin in HIV-Positive Women with Locally Advanced Cervical Cancer (LACC)
AIDS Malignancy Consortium
Ndlovu, Ntokozo
2634791631 X 2264
Phase II – NRG-GY012
A Randomized Phase II Study Comparing Single-Agent Olaparib, Single Agent Cediranib, and the Combination of Cediranib/Olaparib in Women with Recurrent, Persistent or Metastatic Endometrial Cancer
NRG Oncology
Mackay, Helen Jane
(416) 946-2000
Phase III – S1614
A Phase III Randomized Trial of Prophylactic Antiviral Therapy in Patients with Current or Past Hepatitis B Virus (HBV) Infection Receiving Anti-Cancer Therapy for Solid Tumors
SWOG
Hwang, Jessica P.
(713) 745-4516
Phase III – S1802
Phase III Randomized Trial of Standard Systemic Therapy (SST) Versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer
SWOG
Chapin, Brian Francis
(713) 794-5590
Phase Other – AALL18B3-Q
Discovery of the Genetic Basis of ALL in Children with Down Syndrome
Children’s Oncology Group
Rabin, Karen Ruth
(832) 824-4213
Phase Other – AMC-A04
Development of a Health-Related Symptom Index for Spanish-Speaking Persons Diagnosed with and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions (HSIL)
AIDS Malignancy Consortium
Atkinson, Thomas Michael
(646) 888-0089
Phase Other – ECOG-ACRIN-EAQ161CD
Biomarker Testing in Common Solid Cancers: An Assessment of Current Practices in Precision Oncology in the Community Setting
ECOG-ACRIN Cancer Research Group
Trosman, Julia
(224) 619-2900
Phase Other – WF-1801
A Single Arm, Pilot Study of Ramipril for Preventing Radiation-Induced Cognitive Decline in Glioblastoma (GBM) Patients Receiving Brain Radiotherapy
Wake Forest NCORP Research Base
Chan, Michael D.
(336) 713-3600
