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Clinical Roundup

NCI study: Interferon may reduce severity of COVID-19 in people with genetic factors

Researchers from NCI and their collaborators have discovered that people of European and African ancestries who were hospitalized for COVID-19 are more likely to carry a particular combination of genetic variants in a gene known as OAS1 than patients with mild disease who were not hospitalized. 
July 15, 2022
Vol.48 No.28
Clinical Roundup

NCI study: COVID-19 was third leading cause of death in the U.S. in 2020 and 2021

COVID-19 was the third leading cause of death in the United States between March 2020 and October 2021, according to an analysis of national death certificate data by researchers at NCI. 
July 08, 2022
Vol.48 No.27
NCI strategy for evaluating MCED assays may bypass cancer clinical trials groups

NCI strategy for evaluating MCED assays may bypass cancer clinical trials groups

NCI is moving forward with a plan to evaluate multi-cancer early detection tests, a technology that is rapidly making inroads into the healthcare system.  
June 24, 2022
Vol.48 No.25
By Paul Goldberg and Alice Tracey
NCI BSA approves eight new, nine reissued concepts

NCI BSA approves eight new, nine reissued concepts

The NCI Board of Scientific Advisors unanimously approved eight new concepts and nine reissued concepts at a meeting June 13-15. 
June 24, 2022
Vol.48 No.25
By Alice Tracey
Julie Bauman: Washington, DC, needs one more NCI-designated cancer center­—and it matters that a woman runs it
Conversation with The Cancer Letter

Julie Bauman: Washington, DC, needs one more NCI-designated cancer center­—and it matters that a woman runs it

As she was interviewing for the director’s job at the George Washington Cancer Center, Julie E. Bauman was asked what her biggest fear would be.
June 17, 2022
Vol.48 No.24
By Paul Goldberg
NCI, CRUK award $100M in Cancer Grand Challenge grants

NCI, CRUK award $100M in Cancer Grand Challenge grants

NCI and Cancer Research UK have awarded $100 million in total funding through the Cancer Grand Challenges program, supporting research into solid tumors in children, cachexia, extrachromosomal DNA, and tumor development.
June 17, 2022
Vol.48 No.24
By Alice Tracey
Doug Lowy: NCI to fund MCED research, early-stage investigator diversity in Moonshot 2.0
NCI

Doug Lowy: NCI to fund MCED research, early-stage investigator diversity in Moonshot 2.0

In the next phase of the Cancer Moonshot, NCI will focus on investing in the development and testing of new modalities, including multi-cancer early detection assays, and fostering diversity in oncology, NCI Acting Director Douglas R. Lowy said at a joint meeting of the Board Of Scientific Advisors and the National Cancer Advisory Board.
June 17, 2022
Vol.48 No.24
By Alice Tracey
ANCHOR trial shows that treatment of anal high-grade squamous intraepithelial lesions prevents anal cancer in people with HIV
Trials & Tribulations

ANCHOR trial shows that treatment of anal high-grade squamous intraepithelial lesions prevents anal cancer in people with HIV

Before the results of the ANal Cancer/HSIL Outcomes Research (ANCHOR) study became available earlier this week, there was no clear reason to screen for the anal cancer precursor, anal high-grade squamous intraepithelial lesions (HSIL).  
June 17, 2022
Vol.48 No.24
By Joel M. Palefsky and Robert Yarchoan
Lowy calls for expanding NCI’s clinical impact, including: (1) the number of drug candidates, (2) the clinical trials system, and (3) access to cancer care

Lowy calls for expanding NCI’s clinical impact, including: (1) the number of drug candidates, (2) the clinical trials system, and (3) access to cancer care

NCI must make a bigger investment in new cancer therapies and expand the clinical trials system that tests them, the institute’s Acting Director Douglas Lowy said in his remarks at the American Society of Clinical Oncology annual meeting June 4.
June 10, 2022
Vol.48 No.23
By Alice Tracey
Wake Forest CCSG cut from 5 years to 3 as center changes leadership, administrative structure

Wake Forest CCSG cut from 5 years to 3 as center changes leadership, administrative structure

NCI has truncated the just-renewed five-year Cancer Center Support Grant held by Wake Forest Baptist Comprehensive Cancer Center as that institution undergoes a bumpy transition of leadership—in the midst of a challenging integration with Atrium Health Levine Cancer Institute.
May 27, 2022
Vol.48 No.21
By Paul Goldberg

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