NCI Trials for August 2022

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The National Cancer Institute approved the following clinical research studies last month.  

For further information, contact the principal investigator listed.


Phase II – NRG-HN010

A Controlled, Randomized Phase II Trial of Docetaxel Plus Trastuzumab Versus Ado-Trastuzumab Emtansine for Recurrent, Metastatic, or Treatment-Naïve, Unresectable HER2-Positive Salivary Gland Cancer 

NRG Oncology
Ho, Alan Loh
(646) 608-3774


Phase II – S1900F

A Randomized Phase II Study of Carboplatin and Pemetrexed with or Without Selpercatinib (LY3527723) in Participants with Non-Squamous RET Fusion-Positive Stage IV Non-Small Cell Lung Cancer and Progression of Disease on Prior RET Directed Therapy (Lung-MAP Sub-Study)

SWOG
Gray, Jhanelle E.
(813) 745-6895


Phase III – AMC-114

A Phase III, Randomized, Open-Label, Non-Inferiority Study of Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-Related Kaposi Sarcoma in Resource-Limited Settings

AIDS Malignancy Consortium
Krown, Susan E.
44-793-518-3920


Phase III – NRG-CC010

A Phase III Trial Of The Impact Of Sentinel Lymph Node Mapping On Patient Reported Lower Extremity Limb Dysfunction In Endometrial Cancer

NRG Oncology
Tanner, Edward J.
(312) 472-0120


Phase Pilot – PEPN22P1

A Pharmacokinetic Study of VinCRIStine in Infants Dosed According to BSA-Banded Infant Dosing Tables and Older Children Dosed by Traditional BSA Methods

Pediatric Early Phase Clinical Trial Network
Blauel, Emily
(267) 254-2851

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The U.S. House of Representatives Jan. 22 passed a three-bill minibus package that is expected to be the grand finale of the drama of the fiscal year 2026 appropriations process. The package, which funds the HHS as well as the departments of Defense, Transportation, Housing and Urban Development, Labor, and Education, gives NIH and NCI modest raises over FY25, and nullifies several  aggressive cuts the White House had proposed for NIH.

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