NCI Trials for August 2022

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The National Cancer Institute approved the following clinical research studies last month.  

For further information, contact the principal investigator listed.


Phase II – NRG-HN010

A Controlled, Randomized Phase II Trial of Docetaxel Plus Trastuzumab Versus Ado-Trastuzumab Emtansine for Recurrent, Metastatic, or Treatment-Naïve, Unresectable HER2-Positive Salivary Gland Cancer 

NRG Oncology
Ho, Alan Loh
(646) 608-3774


Phase II – S1900F

A Randomized Phase II Study of Carboplatin and Pemetrexed with or Without Selpercatinib (LY3527723) in Participants with Non-Squamous RET Fusion-Positive Stage IV Non-Small Cell Lung Cancer and Progression of Disease on Prior RET Directed Therapy (Lung-MAP Sub-Study)

SWOG
Gray, Jhanelle E.
(813) 745-6895


Phase III – AMC-114

A Phase III, Randomized, Open-Label, Non-Inferiority Study of Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-Related Kaposi Sarcoma in Resource-Limited Settings

AIDS Malignancy Consortium
Krown, Susan E.
44-793-518-3920


Phase III – NRG-CC010

A Phase III Trial Of The Impact Of Sentinel Lymph Node Mapping On Patient Reported Lower Extremity Limb Dysfunction In Endometrial Cancer

NRG Oncology
Tanner, Edward J.
(312) 472-0120


Phase Pilot – PEPN22P1

A Pharmacokinetic Study of VinCRIStine in Infants Dosed According to BSA-Banded Infant Dosing Tables and Older Children Dosed by Traditional BSA Methods

Pediatric Early Phase Clinical Trial Network
Blauel, Emily
(267) 254-2851

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Howard Hughes Medical Institute Investigator David R. Liu was awarded the 2025 Breakthrough Prize in Life Sciences for developing two gene-editing technologies—known as base editing and prime editing—which enable the correction or replacement of virtually any genetic mutation, including those that cause countless human genetic diseases. 

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