Vol.

No.

September 06, 2024Sep 06, 2024

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Lei Zheng got his PhD in San Antonio; now he returns as cancer center director at Mays

Cover Story

Conversation with The Cancer Letter

Lei Zheng got his PhD in San Antonio; now he returns as cancer center director at Mays

By Paul Goldberg

In 1996, Lei Zheng, a graduate of Peking Union Medical College, enrolled in the doctorate program at what was then known as the Cancer Therapy & Research Center in San Antonio.

NCI Director's Report

As NCI’s appropriations stay flat, Rathmell keeps the FY26 bypass budget steady at just under $11.5B
Rathmell: “We understand that there are real economic constraints facing our country and the world. But our gap just can’t keep widening.”

By Jacquelyn Cobb

Clinical Trials & Tribulations

Is gastrectomy indicated?
A study recently published in JAMA suggests lower lifetime gastric cancer risk for CDH1 mutation carriers. Will this lead to changes in management recommendations?

By Rebecca Sutphen, Sue Friedman and Jon Florin

Cancer History Project Conversation with The Cancer Letter Free

Lung cancer couldn’t slow down physician and athlete Lawrence Phillips

By Deborah Doroshow and McKenzie Prillaman

Free In the Archives

Huiping Liu discusses mentorship, translational research on the UChicago Cancer Luminaries podcast

In Brief

Laurie Glimcher to step down as Dana-Farber president and CEO, Benjamin Levine Ebert named successor

ARPA-H to award up to $150M to develop novel technologies for precise tumor removal 

UIUC receives $18.7M from ARPA-H to develop platform for rapid manufacturing of tumor models

McKesson to acquire controlling stake in Florida Cancer Specialists & Research Institute’s Core Ventures

Florida Cancer Specialists & Research Institute, Paradigm Health collaborate to expand patient access to clinical trials

Simon Nazarian named chief digital and technology officer at City of Hope

Omer Awan named vice president and chief information officer at Fred Hutch

Jonathan Sherman named chief of neurosurgical oncology at Rutgers Cancer Institute

Abhisek Swaika named medical director of Northwell at Rego Park, chief of hem/onc at Jewish Forest Hills Hospital

UCSF Prostate Cancer Program receives $7M SPORE grant

NCI funds a $3.7M effort to develop AI that predicts breast cancer risk while addressing health disparities

Hawai’i’s Michele Carbone, Haining Yang receive $2.5M NCI grant for mesothelioma research

Washington University in St. Louis receives $2M from CureSearch for pediatric brain cancer phase I study

Funding Opportunities

DOD Glioblastoma Research Program anticipated funding opportunities for FY24

Clinical Roundup

Monjuvi improves PFS in r/r follicular lymphoma in phase III trial

Longitudinal observational study reveals novel genetic markers of MM progression

Observational genetic study identifies unique types of MM

Kidney cancers rely on mitochondrial metabolism to metastasize, UTSW study shows

UTSW study reveals widespread disparities in immunotherapy use for patients with advanced kidney and bladder cancers

Misetionamide shows promising antitumor effects in ovarian cancer, preclinical study shows

Esopredict test helps ID patients at high risk of esophageal cancers

Study confirms AI outperforms conventional methods for prostate cancer ECE

Drugs & Targets

FDA approves Rybrevant + Lazcluze for NSCLC

FDA approves neoadjuvant/adjuvant Imfinzi for resectable NSCLC

FDA accepts Bristol Myers Squibb’s sBLA for Opdivo + Yervoy in unresectable HCC

FDA grants Imfinzi priority review and Breakthrough Therapy designation for limited-stage SCLC

NCCN adds Lymphir to Clinical Practice Guidelines in Oncology

EC approves Padcev + Keytruda for advanced urothelial cancer

EC approves Ordspono to treat r/r FL or r/r DLBCL

EC approves Lynparza + Imfinzi for pMMR endometrial cancer

EC grants conditional marketing authorization for Tepkinly for r/r FL

NCI Trials

NCI Trials for September 2024

The National Cancer Institute approved the following clinical research studies last month.

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