Diane Simeone begins work as director of Moores Cancer Center on April 1

UCSD researchers engineer novel antibody that triggers anti-tumor response

Researchers at the UC San Diego School of Medicine engineered a new anti-αvβ3 antibody that activates macrophages—a type of immune cell already abundant in advanced αvβ3+ tumors—and were able to trigger anti-tumor responses in both patient tumor samples and in mouse models.

October 17, 2025

Vol.51 No.38

Clinical Roundup

Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic, and triple-negative breast cancer in mice.

October 17, 2025

Vol.51 No.38

KRAS pioneer and Stephenson Prize winner Frank McCormick aims to prevent all KRAS cancers with a pill

In 1988, Frank McCormick learned with the rest of the field that more than 90% of patients with pancreatic cancer have a mutation in the Kirsten rat sarcoma viral gene.

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts that appear to support the survival and growth of malignant tumors.

October 10, 2025

Vol.51 No.37

Funding Opportunities

Project Purple announces research grant to sustain pancreatic cancer studies that have been disrupted by federal funding policy changes

Project Purple, a national nonprofit dedicated to empowering the fight against pancreatic cancer, is launching the Pancreatic Cancer Research Recovery Support Grant. The initiative provides up to two years of bridge or rescue funding for promising pancreatic cancer research projects that were disrupted due to administrative funding policy changes at major federal agencies such as the NIH, the Department of Defense, or the National Science Foundation.

September 26, 2025

Vol.51 No.35

Clinical Roundup

Oral microbes linked to increased risk of pancreatic cancer

Twenty-seven species of bacteria and fungi, among the hundreds that live in people’s mouths, have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, according to a study led by NYU Langone Health and its Perlmutter Cancer Center.

September 19, 2025

Vol.51 No.34

Diane Simeone begins work as director of Moores Cancer Center on April 1

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UCSD researchers engineer novel antibody that triggers anti-tumor response

Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

KRAS pioneer and Stephenson Prize winner Frank McCormick aims to prevent all KRAS cancers with a pill

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

Project Purple announces research grant to sustain pancreatic cancer studies that have been disrupted by federal funding policy changes

Oral microbes linked to increased risk of pancreatic cancer

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