Ted Schwartz family gifts $15M to City of Hope to accelerate immunotherapy research

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Ted Schwartz, a cancer survivor, gifted $15M to City of Hope that will be used entirely to further accelerate immunotherapy research and treatment innovations, such as the CAR T-cell therapy that saved his life. 

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Scientists at the Wistar Institute have identified a combination treatment that overcomes two of the biggest barriers to immunotherapy in glioblastoma. The researchers showed that reprogramming myeloid cells, a type of immune cell that glioblastoma tumors co-opt to protect themselves, while simultaneously boosting cancer-fighting T cells shrank the tumors and prevented them from coming back.
Researchers from City of Hope have developed a “plug-and-play” technology that adds engineered molecules to chimeric antigen receptor T cells after treatment, allowing scientists to better control the cells and redirect them to attack different types of cancer. The preclinical study offers a more flexible way to help CAR T cells keep pace with mutating tumors.

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