Jeffrey M. Rosen will receive the William L. McGuire Memorial Lecture Award at the 2022 San Antonio Breast Cancer Symposium, to be held Dec. 6-10, 2022.
Rosen will present a lecture titled “Leveraging Preclinical Models for Translational Breast Cancer Research” during the symposium.
The William L. McGuire Memorial Lecture Award was established in 1992 to commemorate McGuire’s contributions to breast oncology. McGuire, along with Charles A. Coltman, founded SABCS in 1977.
Rosen is a distinguished service professor of molecular and cellular biology and the co-leader of the breast cancer program at the Dan L Duncan Comprehensive Cancer Center of Baylor College of Medicine.
Rosen is being recognized for his contributions to preclinical and translational breast cancer research, and for his commitment to transdisciplinary collaboration and mentoring of early-career scientists.
Throughout his 53-year career, Rosen has focused on understanding hormonal regulation of mammary gland development, tumorigenesis, and milk production; developing widely used animal models to study normal development and tumorigenesis of the breast; elucidating the mechanisms underlying self-renewal and differentiation of mammary stem cells and cancer stem cells; clarifying the roles of epithelial-to-mesenchymal transition in breast cancer metastasis and therapeutic resistance; and characterizing the tumor immune microenvironment associated with different subtypes of breast tumors.
Rosen joined the faculty at Baylor College of Medicine in 1973 and was a founding member of the Department of Cell Biology. While on sabbatical in the laboratory of George Stark, Rosen was involved in the early studies that elucidated the mechanisms of interferon action, which helped lead to the discovery of the JAK/STAT pathway. In addition, Rosen has mentored more than 100 graduate students, postdoctoral fellows, and junior faculty members.
Rosen was elected a Fellow of the American Academy of Arts and Sciences in 2015. He received the American Association for Cancer Research Distinguished Lectureship in Breast Cancer Research in 2017, the Susan G. Komen Brinker Basic Science Award in 2010, the Michael E. DeBakey, MD, Excellence in Research Award in 2004, and the Barbara & Corbin J. Robertson Jr. Presidential Award for Excellence in Education in 2002, among others.
