Issue 17 - Apr 26, 2019
Issue 16 - Apr 19, 2019
  • Real World Evidence

    How FDA, Pfizer, and Flatiron Health did it

    Approval of Ibrance for men affords a glance at use of real world data

    Real world data played a role in FDA’s recent decision to expand the indications for Pfizer’s drug Ibrance (palbociclib) to include men.

  • NCI advisors approve eight concepts, including three Cancer Moonshot concepts

    The NCI Board of Scientific Advisors approved eight new Requests for Applications, Requests for Proposals, and PAR—a program announcement reviewed in the institute—concepts at a meeting March 25, including three new Cancer Moonshot concepts.

  • Letters to the Editor

    The Cancer Letter is grateful to Mr. Fotopoulos and Mr. Thomson for writing to us.

    Because of incorrect information provided to us, The Cancer Letter reported erroneously that  Dr. Stephen Chagares had performed two robotic mastectomies without a protocol (The Cancer Letter, April 5).

  • In Brief

    • William Cance named interim director of University of Arizona Cancer Center as Andrew Kraft steps down
    • Jefferson, Temple extend due diligence period for negotiations over sale of Fox Chase
    • Dany Habr named chief medical officer at Pfizer Oncology
    • Lisa Kachnic named chair of Columbia Department of Radiation Oncology, chief of Radiation Oncology Service at NY-Presbyterian/Columbia University Irving Medical Center
    • ASCO & The Conquer Cancer  Foundation announce merit awards
    • IMF co-founders Susie and Brian Durie receive honorary doctorate from Vrije Univesiteit Brussel
    • Margo Shoup to join Western Connecticut Health Network as network chair of cancer service line
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  • Clinical Roundup

    • ACP screening guidance calls for two-year interval between mammograms for women at average breast cancer risk
    • Artificial intelligence performs as well as experienced radiologists in detecting prostate cancer
    • Mount Sinai launches clinical trial of new imaging device for head and neck cancer surgeries
    • Cervical cancer subtype rising in some sub-populations
  • Drugs & Targets

    • FDA approves Balversa for urothelial carcinoma with FGFR genetic alterations
    • FDA expands pembrolizumab indication for first-line treatment of NSCLC
    • Aprea Therapeutics receives FDA Fast Track and Orphan Drug designations for APR-246 for MDS
    • Intensity Therapeutics receives Fast Track designation for development of INT230-6 in breast cancer
    • Kitov announces milestone in FameWave acquisition
    • Stanford partners with  Notable and Tempus to make rapid personalized treatment in blood cancer patients
    • OncoSec anounces collaboration with Duke to study TAVO + plasmid DNA vaccines in breast cancer
    • Roswell Park selects Circuit Clinical as collaborator for CIMAvax clinical trial
Issue 15 - Apr 12, 2019
  • Your PBM primer: Senate Finance Committee hearing focuses on the mysteries of pharmacy benefit managers—their power and role in rising drug prices

    Pharmacy benefit managers, like climate change, germs and, possibly, God, are all around, and if we could clear a few hours, it would be good to learn enough about them to sustain a cocktail party conversation.

  • Conversation with The Cancer Letter

    Fred Hirsch: New center focuses Mount Sinai’s thoracic oncology programs

    Every year, 800 to 1,000 new patients get referred to The Tisch Cancer Insitute of Mount Sinai lung cancer specialists.

  • An Appreciation

    Paul Godley, oncologist and disparities researcher, dies at 61

    Paul Godley died after a brief illness on March 31. He was the Rush S. Dickson Distinguished Professor of Hematology and Oncology in the School of Medicine, a professor of epidemiology at the Gillings School of Global Public Health, and senior fellow at the Sheps Center for Health Services Research at the University of North Carolina, Chapel Hill.

  • An Appreciation

    Robert Hickman, inventor of the Hickman catheter, dies at 92

    Robert O. Hickman, a pediatric nephrologist and inventor of a catheter that revolutionized care for cancer patients, died on April 4. He was 92.

  • Corrections

    story about robotic mastectomy that appeared in the April 5 issue of The Cancer Letter reported incorrectly that surgeon Stephen A. Chagares had performed robotic mastectomies at Monmouth Medical Center without a surgical trial protocol.

  • In Brief

    • Walter Stadler replaces Susan Cohn as UChicago Dean for Clinical Research; Sonali Smith steps in as interim chief of hem/onc
    • Michael Harrington named EVP and CFO at MSK
    • Ronan Kelly named chief of oncology for North Texas at Baylor Scott & White Health
    • Christine Rini named director of the Cancer Survivorship Institute of the Northwestern Lurie Cancer Center
    • Kathy Albain and Eva Bading honored at Stritch Awards dinner
    • Beverly Teicher named editor-in-chief of AACR’s Molecular Cancer Therapeutics
    • Elizabeth Platz named editor-in-chief of AACR’s Cancer Epidemiology, Biomarkers & Prevention
    • Gateway for Cancer Research gives $1.5M grant for pediatric brain cancer study at Phoenix Children’s Hospital
    • ACLF and LCA merge to create CO2 Foundation for Lung Cancer
  • Funding Opportunities

    DoD Melanoma Research Program funding opportunities for FY19

    The FY19 Defense Appropriation provides $10 million to the Department of Defense Melanoma Research Program to support innovative, high-impact melanoma research.

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  • Clinical Roundup

    • CDC issues key clarification on guideline for prescribing opioids for chronic pain
    • Study: Targeted drug delivery associated with a reduction in health care utilization and cost
    • ASCO forms task force to address rural cancer care gap
    • Survey finds gap between trial availability and patient need in glioblastoma
    • Roswell Park moves forward with expanded study of CIMAvax
  • Drugs & Targets

    • FDA expands pembrolizumab indication for first-line treatment of NSCLC
    • Lynparza approved in EU in breast cancer
    • FDA approves labeling change for Soltamox
    • American Cancer Society study shows need to better identify who may not benefit from aggressive treatment
  • NCI Trials

    NCI Trials for April

    The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month.