The Cancer Letter

Inside information on cancer research and drug development

Drugs & Targets

FDA grants Rare Pediatric Disease Designation to ABT-414

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FDA granted a Rare Pediatric Disease Designation to ABT-414, an investigational antibody drug conjugate targeting the epidermal growth factor receptor for the treatment of pediatric patients with EGFR-amplified Diffuse Intrinsic Pontine Glioma, known to be highly aggressive and difficult to treat brain tumors found at the base of the brain. According to AbbVie, the drug’s...

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