SWOG DMC says PEGPH20 unlikely to demonstrate OS improvement

KRAS pioneer and Stephenson Prize winner Frank McCormick aims to prevent all KRAS cancers with a pill

In 1988, Frank McCormick learned with the rest of the field that more than 90% of patients with pancreatic cancer have a mutation in the Kirsten rat sarcoma viral gene.

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts that appear to support the survival and growth of malignant tumors.

October 10, 2025

Vol.51 No.37

Funding Opportunities

Project Purple announces research grant to sustain pancreatic cancer studies that have been disrupted by federal funding policy changes

Project Purple, a national nonprofit dedicated to empowering the fight against pancreatic cancer, is launching the Pancreatic Cancer Research Recovery Support Grant. The initiative provides up to two years of bridge or rescue funding for promising pancreatic cancer research projects that were disrupted due to administrative funding policy changes at major federal agencies such as the NIH, the Department of Defense, or the National Science Foundation.

September 26, 2025

Vol.51 No.35

Clinical Roundup

Oral microbes linked to increased risk of pancreatic cancer

Twenty-seven species of bacteria and fungi, among the hundreds that live in people’s mouths, have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, according to a study led by NYU Langone Health and its Perlmutter Cancer Center.

September 19, 2025

Vol.51 No.34

Clinical Roundup

Researchers identify key enzyme that pancreatic cancer cells need to obtain vital metabolic nutrients

A team of scientists at Sanford Burnham Prebys and the University of Zurich in Switzerland identified a specific phosphoinositide kinase called PI5P4Kα as critical to supporting the unique demands of pancreatic ductal adenocarcinoma cells.

September 19, 2025

Vol.51 No.34

Clinical Roundup

Off-the-shelf cancer vaccine elicits strong immune response in patients with pancreatic and colorectal cancer

ELI-002 2P, an off-the-shelf cancer vaccine, can trigger powerful and lasting immune responses, and may help prevent or delay cancer recurrence in high-risk patients whose tumors are driven by KRAS mutations, according to a study published in Nature Medicine.

September 05, 2025

Vol.51 No.32

SWOG DMC says PEGPH20 unlikely to demonstrate OS improvement

YOU MAY BE INTERESTED IN

KRAS pioneer and Stephenson Prize winner Frank McCormick aims to prevent all KRAS cancers with a pill

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

Project Purple announces research grant to sustain pancreatic cancer studies that have been disrupted by federal funding policy changes

Oral microbes linked to increased risk of pancreatic cancer

Researchers identify key enzyme that pancreatic cancer cells need to obtain vital metabolic nutrients

Off-the-shelf cancer vaccine elicits strong immune response in patients with pancreatic and colorectal cancer

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