Amgen announced that the Journal of Clinical Oncology published results from the Phase 2, open-label ALCANTARA study evaluating the efficacy and safety of Blincyto (blinatumomab) in patients with Philadelphia chromosome-positive relapsed or refractory B-cell precursor acute lymphoblastic leukemia who had failed at least one second-generation or later tyrosine kinase inhibitor.
Results from the phase I/II multicenter international CADENZA trial, led by researchers at the University of Texas MD Anderson Cancer Center, show that 75% of patients with blastic plasmacytoid dendritic cell neoplasm who were treated with the antibody-drug conjugate pivekimab sunirine had a complete response.
