Phase III Eribulin Trial Boosts OS in Liposarcoma Patients

Only half of adolescents and young adults with cancer get fertility counseling before treatment
Oncofertility consult is an oft-overlooked standard of care

For a year before an osteosarcoma was found in her right proximal tibia, Sammy Ulloa, pushing through pain, persisted with her training as a Division I track and field and cross-country competitor.

April 11, 2025

Vol.51 No.14

By Claire Marie Porter

Clinical Roundup

Keytruda improves outcomes in soft tissue sarcoma

Addition of the immunotherapy drug pembrolizumab (Keytruda) to standard of care for patients with advanced soft tissue sarcoma of the limb significantly improved disease-free survival, according to the results of the SU2C-SARC032 clinical trial led by researchers from the University of Pittsburgh, UPMC, Duke University, and Princess Margaret Cancer Centre.

November 15, 2024

Vol.50 No.43

Clinical Roundup

UCLA investigators develop collection of sarcoma patient-derived organoids for personalized cancer treatments

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to work for each individual patient.

September 27, 2024

Vol.50 No.36

Clinical Roundup

Novel tumor models provide insights into deadly sarcomas

Investigators at UC Davis Comprehensive Cancer Center and UCLA Health’s Jonsson Comprehensive Cancer Center report they have manipulated mesenchymal stem cells to create four different sarcoma models.

September 20, 2024

Vol.50 No.35

Drugs & Targets

FDA grants Orphan Drug designation to elraglusib for soft tissue sarcomas

FDA has granted orphan drug designation for the GSK-3β inhibitor elraglusib, for treatment of soft tissue sarcoma.

September 13, 2024

Vol.50 No.34

Drugs & Targets

FDA grants accelerated approval to afamitresgene autoleucel for unresectable or metastatic synovial sarcoma

FDA has granted an accelerated approval to afamitresgene autoleucel (Tecelra), a melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T-cell immunotherapy, for adults with unresectable or metastatic synovial sarcoma who have received prior chemotherapy, are HLA-A*02:01P, -A*02:02P, -A*02:03P, or -A*02:06P positive and whose tumor expresses the MAGE-A4 antigen as determined by FDA-approved or cleared companion diagnostic devices.

August 02, 2024

Vol.50 No.31

Phase III Eribulin Trial Boosts OS in Liposarcoma Patients

YOU MAY BE INTERESTED IN

Only half of adolescents and young adults with cancer get fertility counseling before treatment
Oncofertility consult is an oft-overlooked standard of care

Keytruda improves outcomes in soft tissue sarcoma

UCLA investigators develop collection of sarcoma patient-derived organoids for personalized cancer treatments

Novel tumor models provide insights into deadly sarcomas

FDA grants Orphan Drug designation to elraglusib for soft tissue sarcomas

FDA grants accelerated approval to afamitresgene autoleucel for unresectable or metastatic synovial sarcoma

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Phase III Eribulin Trial Boosts OS in Liposarcoma Patients

YOU MAY BE INTERESTED IN

Only half of adolescents and young adults with cancer get fertility counseling before treatmentOncofertility consult is an oft-overlooked standard of care

Keytruda improves outcomes in soft tissue sarcoma

UCLA investigators develop collection of sarcoma patient-derived organoids for personalized cancer treatments

Novel tumor models provide insights into deadly sarcomas

FDA grants Orphan Drug designation to elraglusib for soft tissue sarcomas

FDA grants accelerated approval to afamitresgene autoleucel for unresectable or metastatic synovial sarcoma

Only half of adolescents and young adults with cancer get fertility counseling before treatment
Oncofertility consult is an oft-overlooked standard of care