AI-based liquid biopsy may detect liver fibrosis, cirrhosis, and broader chronic disease signals, Johns Hopkins researchers find

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Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence-based liquid biopsy test using genome-wide cell-free DNA fragmentation patterns and repeat landscapes can detect early liver fibrosis and cirrhosis, and may also reveal signals of broader chronic disease burden.

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Malcolm V. Brock, director of Clinical and Translational Research in Thoracic Surgery at Johns Hopkins Kimmel Comprehensive Cancer Center, grew up in Bermuda. His father insisted that his children branch outside the small island—the country has a population of just over 60,000 people—and challenge themselves abroad.

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