Targeted radiation during surgery reduces pancreatic cancer recurrence, Hopkins study finds

Drugs approved for pain also reduce bone cancer growth, Hopkins-led pre-clinical study finds

Federally funded research in mice showed that neurons regulate osteosarcoma progression, suggesting that inhibiting nerve signaling might improve patient outcomes.

October 31, 2025

Vol.51 No.40

Cancer Policy

Revolution Medicines’ pancreatic cancer drug received a new priority voucher from FDA

Earlier this year, FDA announced that it would be initiating a voucher program aimed at accelerating review time for applications that are deemed to be advancing U.S. “national priorities” (The Cancer Letter, June 20, 2025).

October 24, 2025

Vol.51 No.39

By Claire Marie Porter

Clinical Roundup

Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic, and triple-negative breast cancer in mice.

October 17, 2025

Vol.51 No.38

KRAS pioneer and Stephenson Prize winner Frank McCormick aims to prevent all KRAS cancers with a pill

In 1988, Frank McCormick learned with the rest of the field that more than 90% of patients with pancreatic cancer have a mutation in the Kirsten rat sarcoma viral gene.

Five-treatment radiation regimen poised to become standard of care, phase III data show

Men with intermediate-risk prostate cancer can receive a complete course of radiation in just five treatments—rather than the typical 20 to 28—while maintaining excellent cancer control and improving quality of life, according to results of an international phase III trial conducted by Rodney J. Ellis.

October 10, 2025

Vol.51 No.37

Clinical Roundup

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts that appear to support the survival and growth of malignant tumors.

October 10, 2025

Vol.51 No.37

Targeted radiation during surgery reduces pancreatic cancer recurrence, Hopkins study finds

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Drugs approved for pain also reduce bone cancer growth, Hopkins-led pre-clinical study finds

Revolution Medicines’ pancreatic cancer drug received a new priority voucher from FDA

Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

KRAS pioneer and Stephenson Prize winner Frank McCormick aims to prevent all KRAS cancers with a pill

Five-treatment radiation regimen poised to become standard of care, phase III data show

Researchers identify two groups of antigen-presenting fibroblasts that support survival and growth of malignant tumors

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