Neoadjuvant ablative radiotherapy + chemo reduces risk of pancreatic cancer regrowth, stimulates immune system, cohort study finds

Targeted radiation during surgery reduces pancreatic cancer recurrence, Hopkins study finds

Using intraoperative radiation to eliminate pancreatic cancer cells that have spread to areas around the pancreas, investigators at Johns Hopkins have been able to reduce the recurrence rate around the pancreas to 5%.

October 31, 2025

Vol.51 No.40

Clinical Roundup

Researchers develop technique to track chemotherapy drug inside cells

Scientists face limitations in determining the results of drug effectiveness, as well as ensuring even distribution among all cancer cells because of the highly compact nature of tumors. Researchers are working to change that by giving chemotherapy drugs a kind of chemical “signal” to track them inside cells.

October 31, 2025

Vol.51 No.40

Cancer Policy

Revolution Medicines’ pancreatic cancer drug received a new priority voucher from FDA

Earlier this year, FDA announced that it would be initiating a voucher program aimed at accelerating review time for applications that are deemed to be advancing U.S. “national priorities” (The Cancer Letter, June 20, 2025).

October 24, 2025

Vol.51 No.39

By Claire Marie Porter

Clinical Roundup

Study points to potential cause for “chemo brain”

Cancer is a challenging enough diagnosis, but many patients are dealt a second blow, even as they heal: chemo brain.

October 17, 2025

Vol.51 No.38

Clinical Roundup

Kidney cancer drug shows promise against calcium imbalance caused by tumors, UTSW study shows

Elevated calcium levels in the blood—a complication of kidney cancers known as hypercalcemia—may be successfully treated with HIF-2α inhibitors developed by UT Southwestern Medical Center.

October 17, 2025

Vol.51 No.38

Clinical Roundup

Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic, and triple-negative breast cancer in mice.

October 17, 2025

Vol.51 No.38

Neoadjuvant ablative radiotherapy + chemo reduces risk of pancreatic cancer regrowth, stimulates immune system, cohort study finds

YOU MAY BE INTERESTED IN

Targeted radiation during surgery reduces pancreatic cancer recurrence, Hopkins study finds

Researchers develop technique to track chemotherapy drug inside cells

Revolution Medicines’ pancreatic cancer drug received a new priority voucher from FDA

Study points to potential cause for “chemo brain”

Kidney cancer drug shows promise against calcium imbalance caused by tumors, UTSW study shows

Nanoparticle vaccine prevents melanoma, pancreatic, and breast cancers in mice, study finds

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