The Cancer Letter

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Clinical Roundup

Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers

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Precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated PDAC development in mice, according to results of a study published in Cancer Research, a journal of the American Association for Cancer Research.

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