A phase II trial found that for patients with HER2+ metastatic colorectal cancer, dual HER2-inhibitor therapy can be a similarly efficacious but less toxic alternative to EGFR inhibitor therapy. Exploratory analysis suggests greater HER2 amplification in a tumor may be associated with greater clinical benefit of dual HER2 inhibitor vs EGFR inhibitor therapy.
Researchers at the University of Chicago Medicine Comprehensive Cancer Center have discovered that high doses of radiation cause growth in existing metastatic tumors that weren’t directly treated with radiation.
