Scientists uncover protein that helps cancer cells dodge CAR T-cell therapy

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Scientists at City of Hope identified a protein that could help prevent CAR T-cell therapy antigen escape. The research, published in the journal Cell, could lead to more personalized therapies that improve cancer patients’ survival.

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As the chief scientific officer of the Leukemia & Lymphoma Society for the past eleven years, it has been a privilege to lead a group of scientists that has doled out more than $600 million for cutting-edge hematologic oncology research. These dollars went to more than 1,000 research projects through initiatives like our biomedical research grant programs and LLS’s venture philanthropy, the Therapy Acceleration Program (TAP). 
Earlier this week at City of Hope, we celebrated World Cancer Day by announcing ambitious solutions to tackle some of the most pressing challenges in cancer care. This includes groundbreaking advancements in microbiome research aimed at improving cancer survival, increased emphasis on cancers that disproportionately affect women and people of color, and enhanced access to advanced cancer treatment.

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