Pan-cancer proteogenomics reveals potential drug targets

AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution

New research on the possibility to kill TNBCs by hijacking signals that normally drive mammary gland involution was released in Nature.

October 11, 2024

Vol.50 No.38

In Brief

John Ashton named associate director for shared resources at Wilmot Cancer Institute

John M. Ashton, associate professor in the department of biomedical genetics, has been promoted from assistant director to associate director of shared resources at the University of Rochester’s Wilmot Cancer Institute.

September 13, 2024

Vol.50 No.34

Clinical Roundup

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

A study published in Nature reveals the functional relevance of tumor-neuron interactions that regulate the growth of ependymoma brain tumors.

August 02, 2024

Vol.50 No.31

Drugs & Targets

Labcorp, Ultima Genomics collaborate to advance whole genome sequencing applications and oncology testing capabilities

Labcorp announced an expanded collaboration with Ultima Genomics to utilize its UG 100TM sequencing solution and ppmSeqTM technology to explore new whole genome sequencing clinical applications, including molecular residual disease in patients with early-stage solid tumor cancers.

August 02, 2024

Vol.50 No.31

Clinical Roundup

Unexpected role of OTX2 drives aggressive medulloblastoma

Researchers at Baylor College of Medicine, Texas Children’s Hospital, the University of Manitoba, and collaborating institutions revealed an unexpected way in which the protein OTX2 drives the progression of medulloblastoma—the most common aggressive childhood brain cancer.

July 19, 2024

Vol.50 No.29

Clinical Trials & Tribulations

Paired tumor-germline testing can enhance patient care—with guidance from genetics specialists

In May, the American Society of Clinical Oncology released guidelines on the use of germline genetic testing panels in concert with tumor testing for cancer patients. xxx:more

June 07, 2024

Vol.50 No.23

By Rebecca Sutphen