Wistar scientists discover link between leaky gut and accelerated biological aging

Wistar’s Nan Zhang and Noam Auslander receive $1.2M in biomedical research grants from V Foundation

Nan ZhangNoam AuslanderNan Zhang and Noam Auslander, the Wistar Institute assistant professors, have both received independent funding totaling $1.2 million over the next three years for cancer research projects from the V Foundation for Cancer Research. The grants are awarded to cancer researchers deemed “V Scholars” and allow Zhang and Auslander to pursue separate projects aimed at new strategies to improve the effectiveness of certain cancer therapies.

December 13, 2024

Vol.50 No.46

Clinical Roundup

Wistar Institute researchers identify the role of a Parkinson’s disease-related protein in cancer and T-cell activation

The Wistar Institute’s president and CEO, Dario C. Altieri, and his team have demonstrated the role of Parkin—a protein implicated in Parkinson’s disease—in the body’s innate immune response to cancer. Parkin is not expressed in several cancers. Altieri and his team engineered cancer cells to re-express Parkin and found that Parkin contributes to the production of interferons, which activate and attract T cells to fight the tumor. The lab’s findings were published in The Journal of Clinical Investigation.

September 20, 2024

Vol.50 No.35

Tumors are able to form with no DNA mutations, fly study shows

Tumors are able to form without any DNA mutations, according to a recent proof-of-principle study performed in flies. Epigenetic changes alone—even temporary alterations—induced permanent cancer cell fate.

Wistar, Accelerated Biosciences collaborate to develop immune cell therapies

The Wistar Institute is collaborating with Accelerated Biosciences Corp. to create a platform based on human trophoblast stem cells to explore new immunotherapies that use Accelerated Bio’s proprietary technology. This collaboration could generate various types of immune cells from hTSCs, changing the field of allogeneic immunotherapies.

July 12, 2024

Vol.50 No.28

In Brief

Jozef Madzo named director of bioinformatics at Wistar

Jozef Madzo was named director of bioinformatics at the Wistar Institute. He will lead and oversee Wistar’s bioinformatics projects and initiatives across a variety of advanced biomedical research programs.

July 05, 2024

Vol.50 No.27

In Brief

Noam Auslander receives $600K grant to identify connections between gut microbial genes and melanoma immunotherapy

The Wistar Institute’s Noam Auslander, assistant professor in the Molecular and Cellular Oncogenesis Program at the Ellen and Ronald Caplan Cancer Center, was awarded a $600,000 Women Scientists Innovation Award for Cancer Research grant from the V Foundation for Cancer Research.

June 28, 2024

Vol.50 No.26

Wistar scientists discover link between leaky gut and accelerated biological aging

YOU MAY BE INTERESTED IN

Wistar’s Nan Zhang and Noam Auslander receive $1.2M in biomedical research grants from V Foundation

Wistar Institute researchers identify the role of a Parkinson’s disease-related protein in cancer and T-cell activation

Tumors are able to form with no DNA mutations, fly study shows

Wistar, Accelerated Biosciences collaborate to develop immune cell therapies

Jozef Madzo named director of bioinformatics at Wistar

Noam Auslander receives $600K grant to identify connections between gut microbial genes and melanoma immunotherapy

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