Experimental drug combination shows promise against hard-to-treat peripheral nerve sheath tumors

Stephen Baylin and Andrew Feinberg, of Johns Hopkins, win Technion’s Harvey Prize

Stephen BaylinAndrew FeinbergJohns Hopkins University School of Medicine and Johns Hopkins Kimmel Cancer Center researchers Stephen Baylin and Andrew Feinberg were awarded the 2022–2023 Harvey Prize in the field of Science and Technology by the Technion—Israel Institute of Technology.

December 13, 2024

Vol.50 No.46

Clinical Roundup

Keytruda improves outcomes in soft tissue sarcoma

Addition of the immunotherapy drug pembrolizumab (Keytruda) to standard of care for patients with advanced soft tissue sarcoma of the limb significantly improved disease-free survival, according to the results of the SU2C-SARC032 clinical trial led by researchers from the University of Pittsburgh, UPMC, Duke University, and Princess Margaret Cancer Centre.

November 15, 2024

Vol.50 No.43

Clinical Roundup

Scientists identify genes that help cancer cells survive in the bloodstream

Scientists at the Johns Hopkins Kimmel Cancer Center have identified 16 genes that breast cancer cells use to survive in the bloodstream after they’ve escaped the low-oxygen regions of a tumor. Each is a potential therapeutic target to stop cancer recurrence, and one—MUC1—is already in clinical trials. The research was published online Sept. 28 in...

November 08, 2024

Vol.50 No.42

Clinical Roundup

UCLA investigators develop collection of sarcoma patient-derived organoids for personalized cancer treatments

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to work for each individual patient.

September 27, 2024

Vol.50 No.36

Clinical Roundup

Novel tumor models provide insights into deadly sarcomas

Investigators at UC Davis Comprehensive Cancer Center and UCLA Health’s Jonsson Comprehensive Cancer Center report they have manipulated mesenchymal stem cells to create four different sarcoma models.

September 20, 2024

Vol.50 No.35

Clinical Roundup

Immunotherapy before and after lung cancer surgery reduces death risk, disease recurrence

People with operable non-small cell lung cancers may fare better over the next few years by receiving immunotherapy treatments before and after surgery instead of only before surgery, according to an analysis by Johns Hopkins Kimmel Cancer Center investigators.

September 13, 2024

Vol.50 No.34

Experimental drug combination shows promise against hard-to-treat peripheral nerve sheath tumors

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Stephen Baylin and Andrew Feinberg, of Johns Hopkins, win Technion’s Harvey Prize

Keytruda improves outcomes in soft tissue sarcoma

Scientists identify genes that help cancer cells survive in the bloodstream

UCLA investigators develop collection of sarcoma patient-derived organoids for personalized cancer treatments

Novel tumor models provide insights into deadly sarcomas

Immunotherapy before and after lung cancer surgery reduces death risk, disease recurrence

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