Cancer drug targets uncovered using base editing and chemical proteomics

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A team at Scripps Research and the Broad Institute of Harvard and MIT has discovered a new method to hone in on new drug targets most likely to impact multiple cancers.

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Researchers from the Broad Institute of MIT and Harvard, the University of Georgia, and the One Health Company have published the results from the largest-ever genomic sequencing study of canine tumors. The study shows that dog and human cancers are far more genetically similar than previously known and underscores the important role of canine cancer data in accelerating the development of precision treatments for cancer patients of both species.

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