Study reveals immune cells associated with immunotherapy response in HCC

Rare pancreatic cancer shows strong response to immunotherapy

New research shows that a rare group of pancreatic cancer patients responded remarkably well to immunotherapy, a treatment typically considered ineffective for this cancer type.

July 03, 2025

Vol.51 No.26

In Brief

Yuman Fong delivers the Royal College of Surgeons of Edinburgh Lister Legacy Lecture

Yuman Fong, chair of the Department of Surgery at City of Hope, delivered the Lister Legacy Lecture at the triennial conference of The Royal College of Surgeons of Edinburgh. This presentation honors the long-term impact of Baron Joseph Lister, who brought antiseptic techniques to the practice of surgery.

June 27, 2025

Vol.51 No.25

Clinical Roundup

VCU Massey researchers discover TAF2 gene plays a pivotal role in HCC

Devanand Sarkar and a team of scientists at VCU Massey Comprehensive Cancer Center have discovered that the gene TAF2 plays a pivotal role in the growth of hepatocellular carcinoma. The researchers found that TAF2 is overexpressed in HCC patients compared to individuals with healthy livers, and that TAF2 regulates the survival of hepatocytes—the functional cells of the liver—and tumor formation. Their study—recently published in the journal Hepatology also demonstrates that TAF2 cooperates with the MYC gene, another known major driver of cancer, to accelerate tumor growth.

June 27, 2025

Vol.51 No.25

Clinical Roundup

Researchers identify key B-cell lymphoma traits linked with greatest benefit from CD19 CAR T-cell therapy

In the largest study of its kind, researchers from The University of Texas MD Anderson Cancer Center identified three subgroups of patients with large B-cell lymphoma who have different levels of benefit from CD19 chimeric antigen receptor T cell therapy.

June 20, 2025

Vol.51 No.24

Clinical Roundup

Neoadjuvant immunotherapy + chemo regimen significantly improves long-term survival in NSCLC

Adding immunotherapy to chemotherapy before surgery for patients with operable non-small cell lung cancer improved long-term survival overall compared with chemotherapy alone, according to a clinical trial published June 2 in The New England Journal of Medicine and presented at the annual meeting of the American Society of Clinical Oncology.

June 06, 2025

Vol.51 No.22

Clinical Roundup

Wistar scientists uncover new viral mechanism for evading immunity, identifying a new drug target

Researchers at The Wistar Institute have identified a previously unknown mechanism by which viruses can reprogram mitochondrial structure to silence immune responses and ensure successful viral reproduction.

May 23, 2025

Vol.51 No.20

Study reveals immune cells associated with immunotherapy response in HCC

YOU MAY BE INTERESTED IN

Rare pancreatic cancer shows strong response to immunotherapy

Yuman Fong delivers the Royal College of Surgeons of Edinburgh Lister Legacy Lecture

VCU Massey researchers discover TAF2 gene plays a pivotal role in HCC

Researchers identify key B-cell lymphoma traits linked with greatest benefit from CD19 CAR T-cell therapy

Neoadjuvant immunotherapy + chemo regimen significantly improves long-term survival in NSCLC

Wistar scientists uncover new viral mechanism for evading immunity, identifying a new drug target

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