A phase II clinical trial led by Winship Cancer Institute of Emory University showed a combination of Keytruda (pembrolizumab) and Cabometyx (cabozantinib, also known as Cometriq) was well tolerated and benefitted 91% of participating patients with recurrent/metastatic head and neck squamous cell carcinoma.
The European Commission approved Keytruda (pembrolizumab), an anti-PD-1 therapy, as a monotherapy for the treatment of resectable locally advanced head-and-neck squamous cell carcinoma as neoadjuvant treatment, continued as adjuvant treatment in combination with radiation therapy with or without concomitant cisplatin and then as monotherapy in adults whose tumors express PD-L1 with a Combined Positive Score ≥1.
