The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

NCI Center for Cancer Research study identifies ecDNA as driver of SCLC

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Researchers at NCI Center for Cancer Research have identified extrachromosomal DNA as a major driver of small cell lung cancer, highlighting a novel biomarker and therapeutic target that could be used to eliminate the most aggressive and shapeshifting SCLC cells. The study was published in Cancer Discovery.

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