The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Combination therapy targeting angiogenesis drivers demonstrates durable clinical activity in platinum-resistant ovarian cancer

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A phase Ib study by MD Anderson researchers demonstrated that targeting angiogenesis drivers—such as delta-like ligand 4 (DLL4)—may improve responses to vascular endothelial growth factor (VEGF) inhibitors and may lead to improved outcomes in patients with platinum-resistant ovarian cancer (PROC). 

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