SKYSCRAPER-02, the first randomized study of tiragolumab in ES-SCLC, did not meet co-primary endpoint of PFS, Genentech says

Yale receives renewed lung cancer SPORE grant from NCI

Yale Cancer Center’s Specialized Program of Research Excellence in Lung Cancer was awarded a renewal grant from NCI for year 11 of the program.

September 19, 2025

Vol.51 No.34

In Brief

City of Hope expands clinical trial access across U.S. with new national model

City of Hope launched a national clinical trials model to expand access to emerging life-saving cancer treatments to more patients across the country.

September 19, 2025

Vol.51 No.34

Clinical Roundup

Libtayo + chemo shows significant improvement in OS for advanced NSCLC, phase III EMPOWER-Lung 3 trial shows

Libtayo (cemiplimab) plus chemotherapy demonstrates a more than double five-year overall survival rate of 19.4%, compared to 8.8% with chemotherapy alone, according to late-breaking data from exploratory analyses at World Conference on Lung Cancer.

September 19, 2025

Vol.51 No.34

Clinical Roundup

Rezatapopt monotherapy shows confirmed responses of eight solid tumor types in PYNNACLE phase II clinical trial

Rezatapopt monotherapy generated a 33% overall response rate in 97 patients with solid tumors spanning across eight different cancers (ovarian, lung, breast, endometrial, head and neck, colorectal, gallbladder, and ampullary carcinoma) and a median duration of response of 6.2 months, according to PYNNACLE phase II clinical trial interim data. These were patients whose tumors were TP53 Y220C mutated and KRAS wild-type.

September 19, 2025

Vol.51 No.34

Clinical Roundup

Cancer cells can use backup routes to fuel their growth, Van Andel Institute study finds

When it comes to their survival, cancer cells have a host of backup plans.

September 19, 2025

Vol.51 No.34

Drugs & Targets

VieCure, N-Power Medicine partner to expand clinical trial access in community oncology

N-Power Medicine, an oncology drug development company, and VieCure, a company focused on AI-powered oncology intelligence, have announced a partnership to bring N-Power Medicine’s proprietary Kaleido Registry to the VieCure network.

September 19, 2025

Vol.51 No.34

SKYSCRAPER-02, the first randomized study of tiragolumab in ES-SCLC, did not meet co-primary endpoint of PFS, Genentech says

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Yale receives renewed lung cancer SPORE grant from NCI

City of Hope expands clinical trial access across U.S. with new national model

Libtayo + chemo shows significant improvement in OS for advanced NSCLC, phase III EMPOWER-Lung 3 trial shows

Rezatapopt monotherapy shows confirmed responses of eight solid tumor types in PYNNACLE phase II clinical trial

Cancer cells can use backup routes to fuel their growth, Van Andel Institute study finds

VieCure, N-Power Medicine partner to expand clinical trial access in community oncology

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